Spravato (Esketamine)
FDA-approaved relief for depression and anxiety. Covered by many insurances.
Spravato (Esketamine)
FDA-approved treatment for depression and anxiety. Covered by many insurances.
What is Spravato?
Spravato (esketamine) is a brand-name nasal spray containing the active drug esketamine. It is a prescription medication approved by the FDA for treating certain types of depression in adults, specifically treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions. Like intravenous Ketamine, Spravato belongs to a class of drugs called NMDA receptor blockers and is always prescribed in conjunction with at least one other oral antidepressants. It is supplied as a nasal solution in 28 mg sprays and is available in 56 mg and 84 mg dose kits.
What conditions can Spravato treat?
Spravato is FDA approved for patients diagnosed with the following:
Treatment-resistant Depression (TRD)
Treatment-resistant depression (TRD) is a condition where a person's major depressive disorder (MDD) does not adequately respond to at least two different antidepressant treatments, each with sufficient dosage and duration.
Major Depressive Disorder (MDD)
Major depressive disorder (MDD), also known as clinical depression, is a common mental health condition characterized by persistent feelings of sadness, low mood, and loss of interest in activities that were once pleasurable. These symptoms typically last for at least two weeks and can significantly interfere with daily life.
Suicidal Ideations (SI)
Suicidal ideation refers to thinking about or formulating plans for suicide. The ideation exists on a spectrum of intensity, beginning with a general desire to die that lacks any concrete plan or action, and progressing to active ideations involving a detailed plan and intent to act on the ideas.
Your Spravato journey
Free Phone Consultation
Get your questions answered by speaking with on of our intake specialists. You can schedule your phone consultation now.
Safety Clearance & Insurance Authorization
A thorough review by our clinical team will determine the specifics of your protocol. Your in-clinic visits and telehealth integration calls are scheduled.
Spravato Treatment #1
You will receive your first dose of Spravato. This in-clinic visit will take about 2 hours and you will be constantly monitored and supported by our clinical staff.
Integration Support & Check-in
A 1:1 telehealth session approximately 48 hours after your treatment(s) in order to determine whether or not to continue with the treatments.
Spravato Treatments #2 - #8
After your initial integration call we will continue up to 8 Spravato treatments. Each treatment is followed up by a 20-30 minute telehealth integration check-in.
Ongoing Support
Sign up for our community support programs so you can benefit from our out-of-clinic support and continue healing.
Boosters & Ongoing Integration
For some patients more than the initial 8 sesions are needed in order to receive the full benefits of the treatments. We will work with you to determine the appropriate timing of additional Spravato treatments.
Learn more
What is Spravato?
Spravato is a nasal spray medication containing esketamine (Ketamine), used to treat treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal ideations. It is administered in one of our clinics and supervised by licensed clinical staff.
How is the Spravato administered?
Spravato is administered under the supervision of a healthcare provider in our clinics. Patients self-administer the nasal spray and are monitored for at least two hours afterward to manage potential side effects.
What is the dosing schedule for Spravato?
The dosing schedule typically involves twice-weekly treatments for the first month, once-weekly treatments for the second month, and then once every week or two weeks thereafter.
Can I drive after receving Spravato?
No, it is recommended not to drive on the day of the procedure due to potential side effects. Arrange for someone to drive you home and stay with you for the rest of the day if needed.
How long does it take to feel the full effects?
Spravato has been shown to improve depressive symptoms rapidly, often within weeks, making it effective for treatment-resistant cases.
What are the potential side effects of Spravato?
Common side effects include sedation, dissociation, nausea, dizziness, and increased blood pressure. Serious side effects can include problems with thinking clearly and bladder issues.
Can I go back to work the next day?
Yes. However, avoid strenuous activities on the day of the procedure and follow any specific post-procedure instructions from your CIT Clinics provider.
Do I need to fast before the procedure?
Yes, you should avoid food for a certain period before the procedure (typically 6 hours) and clear fluids up to 2 hours before. Specific instructions will be provided during your onboarding process and treatment preparation.
Is Spravato addictive?
While Spravato is a controlled substance due to its potential for abuse, there is no evidence of addiction when used at prescribed doses in a certified medical setting.