doctor research - Clinical Papers & Research

Clinical Papers & Research

Clinical Papers & Research

Antidepressant, mood stabilizing and procognitive effects of very low dose sublingual ketamine in refractory depression

Antidepressant, mood stabilizing and procognitive effects of very low dose sublingual ketamine in refractory depression

Diogo R. Lara, Luisa W. Bisol, Luciano R. MunariInternational Journal of Neuropsychopharmacology, Volume 16, Issue 9, October 2013, ...
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Ketamine—50 years in use: A study

Ketamine—50 years in use: A study

Samuel Kohtala1,2,31Laboratory of Neurotherapeutics, Drug Research Program, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, ...
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Role of Ketamine in the Treatment of Psychiatric Disorders

Role of Ketamine in the Treatment of Psychiatric Disorders

Sahar Derakhshanian, MD, 1 Maxine Zhou, MD, 1 Alexander Rath, MD, 1 Rachel Barlow, BS, 2 Sarah Bertrand, ...
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Low Dose Ketamine Infusion for Posttraumatic Stress Disorder and Chronic Pain

Low Dose Ketamine Infusion for Posttraumatic Stress Disorder and Chronic Pain

Alisher R. Dadabayev,1,2 Sonalee A. Joshi,3 Mariam H. Reda,4 Tamar Lake,1,2 Mark S. Hausman,1,2 Edward Domino,5 and Israel ...
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Ketamine for the acute treatment of severe suicidal ideation

Ketamine for the acute treatment of severe suicidal ideation

Mocrane Abbar, chief of clinical department 1,  Christophe Demattei, statistician 2,  Wissam El-Hage, chief of clinical department 3, ...
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Ketamine for Depression, A Clinical Summary

Ketamine for Depression, A Clinical Summary

Chittaranjan Andrade 11 Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, India. candrade@psychiatrist.com. Chittaranjan Andrade, MDKetamine is an ...
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How the glutathione cycle shapes synaptic glutamate activity

How the glutathione cycle shapes synaptic glutamate activity

  Thomas W Sedlak 1, Bindu D Paul 2, Gregory M Parker 3, Lynda D Hester 2, Adele M Snowman 2, Yu Taniguchi 3, Atsushi Kamiya 3, Solomon H Snyder 1 2 4, Akira Sawa 3Affiliations expandPMID: 30692251PMCID: ...
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SUA-scienceDirect-2021 - Clinical Papers & Research

Effects of intranasal (S)-ketamine on Veterans with co-morbid treatment-resistant depression and PTSD: A retrospective case series

Hewa Artin, Sean Bentley, Eamonn Mehaffey, Fred X. Liu, Kevin Sojourner, Andrew W. Bismark, David Printz, Ellen E. ...
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bps - Clinical Papers & Research

Ketamine treatment for refractory anxiety: A systematic review

Jamie L. Tully, Amelia D. Dahlén, Connor J. Haggarty, Helgi B. Schiöth, Samantha Brooks First published: 04 May ...
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SUA-scienceDirect-2021 - Clinical Papers & Research

Neurocognitive effects of repeated ketamine infusions in comorbid posttraumatic stress disorder and major depressive disorder

C. Sophia Albott, Kelvin O. Lim, Christopher Erbes, Paul Thuras, Joseph Wels, Susanna J.Tye, Paulo R. Shiroma Published ...
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frontiers - Clinical Papers & Research

The Multivariate Effect of Ketamine on PTSD: Systematic Review and Meta-Analysis

Rui Du, Ruili Han, Kun Niu, Jiaqiao Xu, Zihou Zhao, Guofang Lu and Yulong Shang Published 9 March ...
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yalemedicine - Clinical Papers & Research

Ketamine for Adolescent Suicidality

Source: Gerard Sanacora, Yale Medicine The purpose of this study is to determine if intravenous ketamine reduces suicidal ...
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nature - Clinical Papers & Research

Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial

Chadi G. Abdallah, John D. Roache, Ralitza Gueorguieva, Lynnette A. Averill, Stacey Young-McCaughan, Paulo R. Shiroma, Prerana Purohit, ...
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sage - Clinical Papers & Research

Systematic review and meta-analysis of randomized controlled trials of ketamine in the treatment of refractory anxiety spectrum disorders

Elizabeth Whittaker, Alisher R. Dadabayev, Sonalee A. Joshi, Paul Glue Published 15 December 2021| https://doi.org/10.1177/20451253211056743 Abstract Background: Anxiety ...
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nejm1-1 - Clinical Papers & Research

Trial of Psilocybin versus Escitalopram for Depression

N Engl J Med 2021;384:1402-11. DOI: 10.1056/NEJMoa2032994 Robin Carhart‑Harris, Ph.D., Bruna Giribaldi, B.Sc., Rosalind Watts, D.Clin.Psy., Michelle Baker‑Jones, ...
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APJ 2021 - Clinical Papers & Research

Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation

Roger S. McIntyre, M.D., Joshua D. Rosenblat, M.D., M.Sc., Charles B. Nemeroff, M.D., Ph.D., Gerard Sanacora, M.D., Ph.D., ...
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intranasal - Clinical Papers & Research

Comparative Efficacy of Racemic Ketamine and Esketamine for Depression

Journal of Affective Disorders, Volume 281, 15 February 2021, Pages 1001 https://doi.org/10.1016/j.jad.2020.09.071 Anees Bahjiab Gustavo H.Vazqueza Carlos A. ...
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frontiers - Clinical Papers & Research

Ketamine Use for Cancer and Chronic Pain Management

Clayton Culp, Hee Kee Kim and Salahadin Abdi Published 2 February 2021 | https://doi.org/10.3389/fphar.2020.599721 Abstract Ketamine, an N-methyl-D-aspartate ...
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Argel Aguilar-Valles - Clinical Papers & Research

Antidepressant Actions of Ketamine Engage Cell-Specific Translation via eIF4E

Nature (2020). https://doi.org/10.1038/s41467-019-13162-w Argel Aguilar-Valles1,2,3,6 ✉, Danilo De Gregorio1,4, Edna Matta-Camacho1,3, Mohammad J. Eslamizade1,2, Abdessattar Khlaifia2, Agnieszka Skaleka1, ...
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SUA-scienceDirect-2021 - Clinical Papers & Research

The Effects of Ketamine on Cognition in Treatment-Resistant Depression: A Systematic Review and Priority Avenues for Future Research

Hartej Gill, Barjot Gill, Nelson B. Rodrigues, Orly Lipsitz, Joshua Daniel Rosenblat, Sabine El-Halabi, Flora Nasri, Rodrigo B. ...
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journal-clinical-psychiatry - Clinical Papers & Research

A Proof-of-Concept Study of Subanesthetic Intravenous Ketamine Combined With Prolonged Exposure Therapy Among Veterans With Posttraumatic Stress Disorder

Paulo R. Shiroma, MD; Paul Thuras, PhD; Joseph Wels, MD; Christopher Erbes, PhD; Shannon Kehle-Forbes, PhD; and Melissa ...
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SUA-scienceDirect-2021 - Clinical Papers & Research

Neurocognitive impact of ketamine treatment in major depressive disorder: A review on human and animal studies

Camilla Crisanti, Paolo Enrico, Alessio Fiorentini, Giuseppe Delvecchio, Paolo Brambilla Published 29 July 2020 |  https://doi.org/10.1016/j.jad.2020.07.119 Abstract Background ...
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SUA-scienceDirect-2021 - Clinical Papers & Research

The emergence of ketamine as a novel treatment for posttraumatic stress disorder

Adriana Feder, Sarah B. Rutter, Daniela Schiller, Dennis S.Charney Published 19 June 2020 | https://doi.org/10.1016/bs.apha.2020.05.004 Abstract A serious ...
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drinking1 - Clinical Papers & Research

Ketamine Can Reduce Harmful Drinking by “Rewriting” Your Memories

Nat Commun 10, 5187 (2019). https://doi.org/10.1038/s41467-019-13162-w Das, R.K., Gale, G., Walsh, K. et al. Department of Psychiatry, the ...
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Synapse4 - Clinical Papers & Research

Ketamine for Unipolar and Bipolar Depression

Pharmacol. Rep 72, 543–562 (2020). Joanna Kryst, Paweł Kawalec, Alicja Mikrut Mitoraj, Andrzej Pilc, Władysław Lasoń & Tomasz ...
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psilocybin1 - Clinical Papers & Research

Psychedelic Psychiatry’s Brave New World

Cell. Volume 181, Issue 1, P24-28, April 02, 2020 David Nutt, David Erritzoe, and Robin Carhart-Harris Centre for ...
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Rhonda Patrick - Clinical Papers & Research

NAD+ in Aging: What It Is & Why You Need It

  Source: Rhonda Patrick, Found My Fitness In this episode, Rhonda explains what NAD+, why it is ...
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PTSD - Clinical Papers & Research

Study: Ketamine for Chronic Posttraumatic Stress Disorder (PTSD)

AJP in Advance (doi: 10.1176/appi.ajp.2020.20050596 Adriana Feder, M.D., Sara Costi, M.D., Sarah B. Rutter, M.A., Abigail B. Collins, ...
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sinclair and rhonda - Clinical Papers & Research

NAD+ Boosters: How They Slow Aging

  Source: Rhonda Patrick, Found My Fitness Nicotinamide adenine dinucleotide, or NAD+, is a cofactor for multiple physiological ...
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SUA-scienceDirect-2021 - Clinical Papers & Research

Comprehensive assessment of side effects associated with a single dose of ketamine in treatment-resistant depression

Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Dede Greenstein, Christoph Kraus, Bashkim Kadriu, Carlos A. Zarate, Lawrence T. Park ...
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future-medicine - Clinical Papers & Research

How effective is ketamine in the management of chronic neuropathic pain?

Jack Williams Shteamer, Mayson Augustus Callaway, Parth Patel & Vinita Singh Published Online 15 Oct 2019 | https://doi.org/10.2217/pmt-2019-0032 ...
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nature - Clinical Papers & Research

Resting-state brain functional connectivity in patients with chronic pain who responded to subanesthetic-dose ketamine

Yasushi Motoyama, Yoshitetsu Oshiro, Yumiko Takao, Hitoaki Sato, Norihiko Obata, Shinichiro Izuta, Satoshi Mizobuchi & Shigeyuki Kan  Published ...
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JohnsHopkins1-thumbnail - Clinical Papers & Research

Ketamine Isn’t an Opioid, and it Treats Depression in a Unique Way

July 31, 2019 Ketamine has gotten a bad rap as an opioid when there’s plenty of evidence suggesting ...
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springerlink - Clinical Papers & Research

Augmenting the Treatment of PTSD with Ketamine—a Review

Or Duek, Benjamin Kelmendi, Robert H. Pietrzak & Ilan Harpaz-Rotem  Published 10 May 2019 | DOI 10.1007/s40501-019-00172-0 Abstract ...
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Basic RGB - Clinical Papers & Research

Ketamine as Treatment for Post-Traumatic Stress Disorder: A Review

Drugs in Context 2019; 8: 212305. DOI: 10.7573/dic.212305 Felix Liriano1, Candace Hatten MD2, Thomas L Schwartz MD1 1College ...
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ajp.2019 - Clinical Papers & Research

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial

Jennifer L. Phillips, Ph.D., Sandhaya Norris, M.D., Jeanne Talbot, M.D., Ph.D., Meagan Birmingham, M.A., M.B.A., Taylor Hatchard, Ph.D., ...
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KAP1 - Clinical Papers & Research

Ketamine Assisted Psychotherapy (KAP): Demographics, Data, & Outcomes

Journal of Psychoactive Drugs, 51:2, 189-198, DOI: 10.1080/02791072.2019.1587556 Jennifer Dore, Brent Turnipseed, Shannon Dwyer, Andrea Turnipseed, Julane Andries, ...
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LWW - Clinical Papers & Research

Ketamine Infusions for Chronic Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Orhurhu, Vwaire MD, MPH; Orhurhu, Mariam Salisu MD, MPH; Bhatia, Anuj MD, FRCPC; Cohen, Steven P. MD 13 ...
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SUA-scienceDirect-2021 - Clinical Papers & Research

Ketamine: A Paradigm Shift for Depression Research and Treatment

John H. Krystal, Chadi G. Abdallah, Gerard Sanacora, Dennis S. Charney, Ronald S. Duman Published online: 6 March ...
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Anxiety-fpo - Clinical Papers & Research

Ketamine for Treatment-Resistant Mood Disorders

Focus (Am Psychiatr Publ). Winter 2019; 17(1): 8–12. Published online 2019 Jan 7. doi: 10.1176/appi.focus.20180030: 10.1176/appi.focus.20180030 Lawrence T. ...
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synapse3 - Clinical Papers & Research

Magnesium And Ketamine In The Treatment Of Depression

Psychiatria Danubina, 2019; Vol. 31, Suppl. 3, pp 549-553 Natalia Górska, Jakub Slupski, Lukasz P. Szalach, Adam Wlodarczyk, ...
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NIH-logo - Clinical Papers & Research

Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

Maurizio Fava, Marlene P. Freeman, Martina Flynn, Heidi Judge, Bettina B. Hoeppner, Cristina Cusin, Dawn F. Ionescu, Sanjay ...
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happycouple3 - Clinical Papers & Research

How healthy is the healthspan concept?

GeroScience (2018) 40:361–364 https://doi.org/10.1007/s11357-018-0036-9 Matt Kaeberlein Department of Pathology, University of Washington School of Medicine, Seattle, WA 98195, ...
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rapm - Clinical Papers & Research

Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Chronic Pain

Steven P. Cohen, MD; Anuj Bhatia, MBBS, MD; Asokumar Buvanendran, MD; Eric S. Schwenk, MD; Ajay D. Wasan, ...
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mdpi - Clinical Papers & Research

Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder

Carola Rong, Caroline Park, Joshua D. Rosenblat, Mehala Subramaniapillai, Hannah Zuckerman, Dominika Fus, Yena L. Lee, Zihang Pan, ...
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sage - Clinical Papers & Research

Safety and efficacy of maintenance ketamine treatment in patients with treatment-refractory generalised anxiety and social anxiety disorders

Paul Glue, Shona M Neehoff, Natalie J Medlicott, Andrew Gray, Guy Kibby, Neil McNaughton First Published March 21, ...
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depression, man, anxiety

Ketamine for Social Anxiety Disorder

Neuropsychopharmacology. 2018 Jan; 43(2): 325–333. Jerome H Taylor,1,2,3,* Angeli Landeros-Weisenberger,1 Catherine Coughlin,1 Jilian Mulqueen,1 Jessica A Johnson,1 Daniel ...
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AJP3 - Clinical Papers & Research

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

Samuel T. Wilkinson, M.D., Elizabeth D. Ballard, Ph.D., Michael H. Bloch, M.D., M.S., Sanjay J. Mathew, M.D., James ...
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NAD4 - Clinical Papers & Research

How NAD+ Can Treat Degenerative Diseases

ACNEM Journal Vol 35 No 3 – December 2016 Ross Grant1,2,3, Jade Berg1, Nady Braidy4 1Australasian Research Institute, ...
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headache3 - Clinical Papers & Research

Ketamine for the Treatment of Chronic Migraines

The Journal of Headache and Pain (2016) 17:106 DOI 10.1186/s10194-016-0700-3 Clinton Lauritsen1*† , Santiago Mazuera1†, Richard B. Lipton2 ...
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Screen Shot 2021-02-11 at 11.05.32 AM - Clinical Papers & Research

How Ketamine Cures Depression: The Science Behind It

Source: Albert Dahan Like many other drugs, ketamine has multiple effects rendering it suitable for various indications ...
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dendrites - Clinical Papers & Research

Effects of Ketamine on Dendritic Architecture In Vivo in the Mouse Medial Frontal Cortex

ENeuro, March/April 2016, 3(2) e0133-15.2016 1–14  DOI:http://dx.doi.org/10.1523/ENEURO.0133-15.2016 Victoria Phoumthipphavong,1 Florent Barthas,1 Samantha Hassett,1 and Alex C. Kwan1,2 1Department ...
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Portrait of woman holding black and white younger photo of herself - Clinical Papers & Research

Changes in Oxidative Damage, Inflammation and [NAD(H)] with Age

PLoS ONE 9(1): e85335. doi:10.1371/journal.pone.0085335 Jade Guest1,2, Ross Grant2,3*, Trevor A. Mori4, Kevin D. Croft4 1 Australasian Research ...
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Artificial-Synapse - Clinical Papers & Research

Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression

Am J Psychiatry. 2013 October 1; 170(10): 1134–1142. doi:10.1176/appi.ajp.2013.13030392. James W. Murrough, M.D., Dan V. Iosifescu, M.D., Lee ...
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OCD1 - Clinical Papers & Research

Ketamine to Treat Obsessive-Compulsive Disorder (OCD)

Neuropsychopharmacology (2013) 38, 2475–2483 Carolyn I Rodriguez*,1,2, Lawrence S Kegeles1,2, Amanda Levinson2, Tianshu Feng1,2, Sue M Marcus1,2,3, Donna ...
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Screen Shot 2021-02-11 at 11.51.52 AM - Clinical Papers & Research

Ketamine and Depression: From Despair to Hope in Hours

Source: NIH IRP (Intramural Research Program at the National Institutes of Health) Carlos Zarate, M.D., speeds up treatment ...
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Synapse2 - Clinical Papers & Research

Yale University School of Medicine: Ketamine for Depression

Science. 2012 October 5; 338(6103): 68–72. doi:10.1126/science.1222939. Ronald S. Duman* and George K. Aghajanian Departments of Psychiatry and ...
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CRPS3 - Clinical Papers & Research

Ketamine Treats Patients with Complex Regional Pain Syndrome Type 1

Pain 2012; International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. Marnix J. ...
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CRPS1 - Clinical Papers & Research

Duke University: Ketamine for Patients with Complex Regional Pain Syndrome

CNS Drugs 2012; 26 (3): 215-228 1172-7047/12/0003-0215/$49.95/0 Pari Azari, David R. Lindsay, Dean Briones, Collin Clarke, Thomas Buchheit ...
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Collage Of Two Portraits Of The Same Old And Young Man. Face Lif - Clinical Papers & Research

How NAD+ Affects Wistar Rats

PLoS ONE 6(4): e19194. doi:10.1371/journal.pone.0019194 Nady Braidy1, Gilles J. Guillemin1,2, Hussein Mansour3, Tailoi Chan-Ling3, Anne Poljak4, Ross Grant1,5* ...
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CRPS5 - Clinical Papers & Research

Drexel University: Ketamine for Complex Regional Pain Syndrome

PAIN 147 (2009) 107–115 Robert J. Schwartzman *, Guillermo M. Alexander, John R. Grothusen, Terry Paylor, Erin Reichenberger, ...
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CRPS4 - Clinical Papers & Research

Cooper University Hospital: Ketamine for Complex Regional Pain Syndrome

Pain Physician. 2005;8:175-179, ISSN 1533-3159 Michael E. Goldberg, MD, Richard Domsky, MD, Denise Scaringe, MD, Robert Hirsh, MD, ...
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CRPS2 - Clinical Papers & Research

Can Ketamine Treat Complex Regional Pain Syndrome?

PAIN Medicine (2004) Graeme E. Correll, BE, MBBS, FANZCA,* Jahangir Maleki, MD, PhD,† Edward J. Gracely, PhD,‡ Jesse ...
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NAD4 - Clinical Papers & Research

MIT: What Does NAD+ Do?

Current Opinion in Cell Biology 2003, 15:241–246 Su-Ju Lin and Leonard Guarente Department of Biology, Massachusetts Institute of ...
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