Psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking.
Trial of Psilocybin versus Escitalopram for Depression Read More »
Intravenous ketamine appears to be more efficacious than intranasal esketamine for the treatment of depression.
Comparative Efficacy of Racemic Ketamine and Esketamine for Depression Read More »
Sub-anaesthetic doses of ketamine, a noncompetitive N-methyl-d-aspartate receptor antagonist provide rapid and long-lasting antidepressant effects in these patients, but the molecular mechanism of these effects remains unclear.
Antidepressant Actions of Ketamine Engage Cell-Specific Translation via eIF4E Read More »