Sub-anaesthetic doses of ketamine, a noncompetitive N-methyl-d-aspartate receptor antagonist provide rapid and long-lasting antidepressant effects in these patients, but the molecular mechanism of these effects remains unclear.
Antidepressant Actions of Ketamine Engage Cell-Specific Translation via eIF4E Read More »
As converging evidence suggests a role for the glutamate system in the pathophysiology of OCD, we tested whether a single dose of ketamine, a non-competitive N-methyl-D-aspartate (NMDA) glutamate receptor antagonist, could achieve rapid antiobsessional effects.
Ketamine to Treat Obsessive-Compulsive Disorder (OCD) Read More »
Complex Regional Pain Syndrome Type 1 (CRPS-1) responds poorly to standard pain treatment. We evaluated if the N-methyl-D-aspartate receptor antagonist S(+)-ketamine improves pain in CRPS-1 patients.
Ketamine Treats Patients with Complex Regional Pain Syndrome Type 1 Read More »
This randomized double-blind placebo controlled trial was designed to evaluate the effectiveness of intravenous ketamine in the treatment of CRPS.
Drexel University: Ketamine for Complex Regional Pain Syndrome Read More »
Complex Regional Pain Syndrome Type 1 (CRPS-1) responds poorly to standard pain treatment. We evaluated if the N-methyl-D-aspartate receptor antagonist S(+)-ketamine improves pain in CRPS-1 patients.
Cooper University Hospital: Ketamine for Complex Regional Pain Syndrome Read More »
The purpose of this study was to ascertain if indeed the use of subanesthetic inpatient infusions of ketamine provide meaningful improvements in pain scores, and thus, quality of life, in patients suffering from CRPS.
Can Ketamine Treat Complex Regional Pain Syndrome? Read More »