Pain

How Ketamine May Help Pain

In the meantime, practitioners of this new kind of mental healthcare can use ketamine as their psychedelic agent; and some studies, such as the one Grant participated in, are even government funded. The Ketamine for Reduction of Alcoholic Relapse (Kare) study is a novel attempt to ease the huge burden on the NHS caused by alcohol-related illnesses.

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Ketamine Use for Cancer and Chronic Pain Management

Clayton Culp, Hee Kee Kim and Salahadin Abdi Published 2 February 2021 | https://doi.org/10.3389/fphar.2020.599721 Abstract Ketamine, an N-methyl-D-aspartate receptor antagonist, is widely known as a dissociative anesthetic and phencyclidine derivative. Due to an undesirable adverse event profile when used as an anesthetic it had widely fallen out of human use in favor of more modern

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How effective is ketamine in the management of chronic neuropathic pain?

Jack Williams Shteamer, Mayson Augustus Callaway, Parth Patel & Vinita Singh Published Online 15 Oct 2019 | https://doi.org/10.2217/pmt-2019-0032 Abstract The effectiveness of ketamine in treating chronic neuropathic pain, however, remains a debated issue. A recent meta-analysis of double blind randomized controlled trials (DB-RCT) utilizing ketamine for chronic neuropathic pain revealed mixed results. Six studies were

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Resting-state brain functional connectivity in patients with chronic pain who responded to subanesthetic-dose ketamine

Yasushi Motoyama, Yoshitetsu Oshiro, Yumiko Takao, Hitoaki Sato, Norihiko Obata, Shinichiro Izuta, Satoshi Mizobuchi & Shigeyuki Kan  Published 9 September 2019 | https://doi.org/10.1038/s41598-019-49360-1  Abstract Ketamine has been used to treat chronic pain; however, it is still unknown as to what types of chronic pain is ketamine effective against. To identify the effect of administration of

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Ketamine Infusions for Chronic Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Orhurhu, Vwaire MD, MPH; Orhurhu, Mariam Salisu MD, MPH; Bhatia, Anuj MD, FRCPC; Cohen, Steven P. MD 13 March 2019 | doi: 10.1213/ANE.0000000000004185 Abstract BACKGROUND:  IV ketamine is widely used to treat patients with chronic pain, yet the long-term impact remains uncertain. We synthesized evidence from randomized control trials to investigate the effectiveness of IV

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