What is Treatment Resistant Depression?

About 60% of people with depression aren’t helped by the first antidepressant they try, and about 30% don’t respond to several attempts at treatment. Researchers still don’t know why so many don’t people respond well to “anti-depressants” such as SSRIs, SNRIs, etc. Treatment Reistant Depression can be defined as Depression that doesn’t respond to two (or more) different antidepressants from different classes.

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