While NAD supplements are available in some health stores, they are not nearly as effective as receiving NAD intravenously because the compounds are not fully absorbed. The body’s digestive tract and liver break most of the desired compounds down thereby drastically reducing the bioavailability of the NAD (the amount of a drug or supplement that your body can actually use). As a result, oral NAD+ supplements as well as subcutanneous (under the skin) injections of NAD+are much less effective than IV infusions.